Metabolički i oksidacijski stres u konja daljinskog jahanja
Nika Brkljača Bottegaro, DVM, PhD, Assistant Professor
Clinic for Surgery, Orthopaedics and Ophthalmology, Faculty of Veterinary Medicine, University of Zagreb, Croatia; e-mail: firstname.lastname@example.org
Izvor: Knjiga sažetaka 3. međunarodnog veterinarskog specijalističkog simpozija “Hitna i intenzivna skrb u veterinarskoj medicini”
Endurance riding is characterized as a prolonged submaximal aerobic exercise with an increased consumption of oxygen providing energy for homeostasis. Most of the oxygen is reduced and forms carbon dioxide, however, a 1 to 2% of the oxygen forms reactive oxygen species (ROS). Antioxidants prevent oxidant damage by scavenging of ROS, increasing the conversion of less reactive ROS, and facilitating repair of the caused damage. Oxidative stress reflects an imbalance between the systemic manifestation of ROS and a biological system’s anti-oxidative response and can be assessed by measuring different biomarkers. When pro oxidants overcome antioxidative defence, oxidative stress negatively affects health and performance of horses. Oxidative stress causes immediate and/or cumulative deleterious effects contributing to several equine diseases like osteochondrosis disecans, exertional rhabdomyolysis, exercise-induced pulmonary haemorrhage, and degenerative motor neuron disease.
Endurance race induces increased values of selected oxidative stress biomarkers in horses indicating an enhanced oxidative damage. Concurrently, endurance exercise causes an increase in antioxidants as a response to an increased amount of ROS.
Interestingly, an increase in both prooxidants and antioxidants is evident also during shorter, qualification races where younger and less experienced horses are competing.
Since the antioxidant response is more pronounced in relation to endurance races, antioxidant supplementation in sport horses could be beneficial. However, oxidative stress biomarkers are still not completely understood and there are possible physiologic variations that can be influenced by unknown determinates. Besides, in order to better understand the influence of oxidative stress on injuries in endurance horses further studies are needed. Considering the growing interest in this equine discipline it is even
more important to ensure the best possible understanding of the race influence on horse’s body and consequently minimize the negative effects.
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